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Increased expression of coronin-1a in amyotrophic lateral sclerosis: a potential diagnostic biomarker

Frontiers of Medicine 2022, Volume 16, Issue 5,   Pages 723-735 doi: 10.1007/s11684-021-0905-y

Abstract: Therefore, CORO1A might be a potential biomarker and therapeutic target for ALS.

Keywords： amyotrophic lateral sclerosis     coronin-1a     autophagy     pathogenesis    

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iTRAQ-based quantitative analysis of cancer-derived secretory proteome reveals TPM2 as a potential diagnosticbiomarker of colorectal cancer

Yiming Ma,Ting Xiao,Quan Xu,Xinxin Shao,Hongying Wang

Frontiers of Medicine 2016, Volume 10, Issue 3,   Pages 278-285 doi: 10.1007/s11684-016-0453-z

Abstract: In summary, this study revealed potential molecules for future biomarker applications and provided an

Keywords： iTRAQ     secretome     colorectal cancer     TPM2    

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Serum mitochondrial tsRNA serves as a novel biomarker for hepatocarcinoma diagnosis

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 216-226 doi: 10.1007/s11684-022-0920-7

Abstract: However, the diagnostic values and biological functions of circulating tsRNAs, especially for HCC, areIn summary, our study demonstrated that serum tsRNA signature may serve as a novel biomarker of HCC.

Keywords： tsRNA     biomarker     hepatocarcinoma    

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MiRNA-451 is a potential biomarker for estrogenicity in mouse uterus

Lingyan HOU, Yun LU, Ying LI, Li LI

Frontiers of Environmental Science & Engineering 2014, Volume 8, Issue 1,   Pages 99-105 doi: 10.1007/s11783-013-0490-7

Abstract: An alternative way is to evaluate estrogenicity through biomarker genes.MicroRNA (miRNA) is a class of regulatory gene, which has been shown to be a good biomarker for manystrong responses to E2 in the uterus of both immature and overiectomized mice, and could be a potential biomarker

Keywords： estrogen     microRNA (miRNA)     microarray     biomarker    

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High-Throughput Profiling of Serological Immunoglobulin G N-Glycome as a Noninvasive Biomarker Article

Pengcheng Liu, Xiaobing Wang, Aishe Dun, Yutong Li, Houqiang Li, Lu Wang, Yichun Zhang, Cancan Li, Jinxia Zhang, Xiaoyu Zhang, Lixing Ma, Haifeng Hou

Engineering 2023, Volume 26, Issue 7,   Pages 44-53 doi: 10.1016/j.eng.2023.02.008

Abstract: This study aimed to evaluate the diagnostic performance of IgG for gastrointestinal (GI) cancer subtypes

Keywords： Gastrointestinal cancer     Glycosylation     Immunoglobulin G     Diagnostic biomarker    

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Obesity in China: its characteristics, diagnostic criteria, and implications

Weiping Jia

Frontiers of Medicine 2015, Volume 9, Issue 2,   Pages 129-133 doi: 10.1007/s11684-015-0387-x

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Plasma transthyretin is a nutritional biomarker in human morbidities

Frontiers of Medicine 2022, Volume 16, Issue 4,   Pages 540-550 doi: 10.1007/s11684-022-0940-3

Abstract: Transthyretin (TTR) is a small liver-secreted plasma protein that shows close correlations with changes in lean body mass (LBM) during the entire human lifespan and agglomerates the bulk of nitrogen (N)-containing substrates, hence constituting the cornerstone of body building. Amino acids (AAs) dietary restriction causes inhibition of TTR production and impairs the accretion of LBM reserves. Inflammatory disorders result in cytokine-induced abrogation of TTR synthesis and urinary leakage of nitrogenous catabolites. Taken together, the data indicate that malnutrition and inflammation may similarly suppress the production of TTR through distinct and unrelated pathophysiological mechanisms while operating in concert to downsize LBM stores. The hepatic synthesis of TTR integrates both machineries, acting as a marker of reduced LBM resources still available for defense and repair processes. TTR operates as a universal surrogate analyte that allows for the grading of residual LBM capacity to reflect disease burden. Measurement of TTR is a simple, rapid, and inexpensive micro-method that may be reproduced on a daily basis, hence ideally suited for the follow-up of the most intricated clinical situations and as a reliable predictor of any morbidity outcome.

Keywords： lean body mass     nutritional status     transthyretin     malnutrition     inflammation     amyloidosis    

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Biosensor-based assay of exosome biomarker for early diagnosis of cancer

Frontiers of Medicine 2022, Volume 16, Issue 2,   Pages 157-175 doi: 10.1007/s11684-021-0884-z

Abstract: Exosome has recently become an attractive cancer biomarker in noninvasive early diagnosis because of

Keywords： biosensor     exosome     cancer diagnosis    

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Soluble triggering receptor expressed on myeloid cell-1 (sTREM-1): a potential biomarker for the diagnosis

Changlin Cao, Jingxian Gu, Jingyao Zhang

Frontiers of Medicine 2017, Volume 11, Issue 2,   Pages 169-177 doi: 10.1007/s11684-017-0505-z

Abstract: sTREM-1) is a special form of TREM-1 that can be directly tested in human body fluids and well-known biomarkerinfections (e.g., infection), and burn-related infections. sTREM-1 is a more sensitive and specific biomarkerTherefore, sTREM-1 is a feasible biomarker for the targeted therapy and rapid and early diagnosis of

Keywords： soluble triggering receptor expressed on myeloid cells-1     infectious diseases     diagnosis and prognosis     biomarker    

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Meta-analysis of the diagnostic efficiency of frequency-doubling technology for primary glaucoma

LIU Ting, HE Xiangge

Frontiers of Medicine 2007, Volume 1, Issue 1,   Pages 109-114 doi: 10.1007/s11684-007-0021-7

Abstract: The overall diagnostic capabilities and utility of frequency-doubling technology (FDT) in patients withCriteria for inclusion or exclusion were established according to validity criteria for diagnostic studiespublished by the Cochrane Methods Group on Screening and Diagnostic Tests.The included articles are of good quality and FDT can be a highly efficient diagnostic test for primary

Keywords： inclusion     sensitivity analysis     correction     specificity     appropriate    

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Development and application of reconfigurable monitoring and diagnostic system oriented to machine tool

Jing Minqing,Li Meng,Liu Heng

Strategic Study of CAE 2013, Volume 15, Issue 1,   Pages 34-38

Abstract: quot;system engine + function component" architecture for the reconfigurable monitoring and diagnosticThis paper has also developed a series of regular monitoring and diagnostic components for computer numericalThen the monitoring and diagnostic system for specific machine tools, which has been running in

Keywords： monitoring and diagnostic system for machine tool     reconfigurable     system engine     function component    

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An investigation on patient dose in screen-film diagnostic radiology in Lhasa City, Xizang Autonomous

Xiang Du

Frontiers of Medicine 2013, Volume 7, Issue 4,   Pages 506-509 doi: 10.1007/s11684-013-0294-y

Abstract:

This study aimed to investigate patient dose in diagnostic screen-film radiographic examinations in

Keywords： radiation dosage     radiology     radiation protection     radiography/statistics & numerical data    

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Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection

Yu Liao, Yufei Xiang, Zhiguang Zhou

Frontiers of Medicine 2012, Volume 6, Issue 3,   Pages 243-247 doi: 10.1007/s11684-012-0201-y

Abstract: Although it has been reported for about 20 years, the diagnostic criteria of this disease remain controversialHere, we aim to review and discuss the diagnostic criteria of latent autoimmune diabetes in adults.

Keywords： LADA     diagnostic criteria     autoantibodies     insulin independence     age of diagnosis    

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treatment of reproductive diseases and infertility: an overview from the mechanism to the clinic alongside diagnostic

Frontiers of Medicine 2022, Volume 16, Issue 6,   Pages 827-858 doi: 10.1007/s11684-022-0948-8

Abstract: Infertility is experienced by 8%–12% of adults in their reproductive period globally and has become a prevalent concern. Besides routine therapeutic methods, stem cells are rapidly being examined as viable alternative therapies in regenerative medicine and translational investigation. Remarkable progress has been made in understanding the biology and purpose of stem cells. The affected pluripotent stem cells (iPSCs) and mesenchymal stem cells (MSCs) are further studied for their possible use in reproductive medicine, particularly for infertility induced by premature ovarian insufficiency and azoospermia. Accordingly, this study discusses current developments in the use of some kinds of MSCs such as adipose-derived stem cells, bone marrow stromal cells, umbilical cord MSCs, and menstrual blood MSCs. These methods have been used to manage ovarian and uterine disorders, and each technique presents a novel method for the therapy of infertility.

Keywords： infertility     stem cell therapy     mesenchymal stem cells     pluripotent stem cells    

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Real-world fuel consumption of light-duty passenger vehicles using on-board diagnostic (OBD) systems

Xuan Zheng, Sheng Lu, Liuhanzi Yang, Min Yan, Guangyi Xu, Xiaomeng Wu, Lixin Fu, Ye Wu

Frontiers of Environmental Science & Engineering 2020, Volume 14, Issue 2, doi: 10.1007/s11783-019-1212-6

Abstract: • Fuel consumption (FC) from LDPVs is measured using on-board diagnostic method (OBD). • The FC ofThe on-board diagnostic (OBD) approach, which is flexible and offers high-resolution data collection,

Keywords： Fuel consumption     Light-duty passenger vehicles     On-board diagnostic systems    

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Title Author Date Type Operation

Increased expression of coronin-1a in amyotrophic lateral sclerosis: a potential diagnostic biomarker

Journal Article

iTRAQ-based quantitative analysis of cancer-derived secretory proteome reveals TPM2 as a potential diagnosticbiomarker of colorectal cancer

Yiming Ma,Ting Xiao,Quan Xu,Xinxin Shao,Hongying Wang

Journal Article

Serum mitochondrial tsRNA serves as a novel biomarker for hepatocarcinoma diagnosis

Journal Article

MiRNA-451 is a potential biomarker for estrogenicity in mouse uterus

Lingyan HOU, Yun LU, Ying LI, Li LI

Journal Article

High-Throughput Profiling of Serological Immunoglobulin G N-Glycome as a Noninvasive Biomarker

Pengcheng Liu, Xiaobing Wang, Aishe Dun, Yutong Li, Houqiang Li, Lu Wang, Yichun Zhang, Cancan Li, Jinxia Zhang, Xiaoyu Zhang, Lixing Ma, Haifeng Hou

Journal Article

Obesity in China: its characteristics, diagnostic criteria, and implications

Weiping Jia

Journal Article

Plasma transthyretin is a nutritional biomarker in human morbidities

Journal Article

Biosensor-based assay of exosome biomarker for early diagnosis of cancer

Journal Article

Soluble triggering receptor expressed on myeloid cell-1 (sTREM-1): a potential biomarker for the diagnosis

Changlin Cao, Jingxian Gu, Jingyao Zhang

Journal Article

Meta-analysis of the diagnostic efficiency of frequency-doubling technology for primary glaucoma

LIU Ting, HE Xiangge

Journal Article

Development and application of reconfigurable monitoring and diagnostic system oriented to machine tool

Jing Minqing,Li Meng,Liu Heng

Journal Article

An investigation on patient dose in screen-film diagnostic radiology in Lhasa City, Xizang Autonomous

Xiang Du

Journal Article

Diagnostic criteria of latent autoimmune diabetes in adults (LADA): a review and reflection

Yu Liao, Yufei Xiang, Zhiguang Zhou

Journal Article

treatment of reproductive diseases and infertility: an overview from the mechanism to the clinic alongside diagnostic

Journal Article

Real-world fuel consumption of light-duty passenger vehicles using on-board diagnostic (OBD) systems

Xuan Zheng, Sheng Lu, Liuhanzi Yang, Min Yan, Guangyi Xu, Xiaomeng Wu, Lixin Fu, Ye Wu

Journal Article